Effect of Different Polymer Concentration on Bio-Adhesion of Antihypertensive Bio-Adhesive Layer
Asian Resonance (P: ISSN No. 0976-8602 RNI No.UPENG/2012/42622 VOL.-IV, ISSUE-II, April-2015 E: ISSN No. 2349-9443 ) Abstract Aadesh Kumar Assistant Professor, Deptt. of Pharmaeutical Sciences, Kumaun University Block Road, Bhimtal Nainital, Uttarakhand Tanuj Joshi Assistant Professor, Deptt. of Pharmaeutical Sciences, Kumaun University Block Road, Bhimtal Nainital, Uttarakhand Govind Rajpal Teaching Personnel, Roorkee College of Pharmacy, Roorkee, Uttarakhand The term bioadhesion refers to any bond formed between two biological surfaces or a bond between a biological and a synthetic surface. Bio-adhesive system layer will adhere on gastric mucus which can provide significant of gastro-retentive system. Gastric retention will provide advantages such as the delivery of drugs with narrow absorption windows in the small intestinal region. Also, longer residence time in the stomach could be advantageous for local action in the upper part of the small intestine, ...