Effects of Supervised Exercise Training on Cardiopulmonary Functions and Quality of Life Outcomes in Breast Cancer Patients; Randomized Controlled Trial

Periodic Research (P: ISSN No. 2231-0045 RNI No. UPBIL/2012/55438 VOL.-8, ISSUE-4 May -2020 E: ISSN No. 2349-9435) Paper Submission: 15/05/2020, Date of Acceptance: 26/05/2020, Date of Publication: 28/05/2020

 Abstract

Ella Jain 

MPTh (Cardiopulmonary) Jamia Hamdard, New Delhi, India

Rajeev Aggarwal 

Physiotherapist, Neuro Sciences Centre, AIIMS, New Delhi, India

Faizan Ahmad 

Assistant Professor, FAHS, Jamia Hamdard, New Delhi, India

Deepika Dhamija

 Physiotherapist, Dharamshila Hospital and Research Centre, New Delhi, India 

                                                 

Background: Breast is the commonest site of cancer in females. With new advanced and more efficient surgical and medical treatments the survival rate has improved. The adverse effects of cardiotoxic nature of adjuvant therapies results in depreciated cardio pulmonary capacity and worsening quality of life. Purpose: To determine the effects of exercise training on cardiopulmonary function and quality of life in stage II and III breast cancer survivors who had completed surgery (modified radical mastectomy-MRM), chemotherapy and are currently on radiation therapy. Methods: 30 Breast cancer patients were randomly assigned to an exercise (n=15) or control (n=15) group. The exercise group received exercise training thrice a week at initiating intensity of 13 RPE upto 15 RPE in time frame of 4 weeks. The control group did not train but was at conventional treatment as at DHRC. The primary outcomes were changes in peak oxygen consumption and overall quality of life from baseline to post intervention. Peak VO2 was assessed by submaximal exercise Half mile walk test and quality of life by using SF-36 questionnaire. Results: All 30 patients completed the trial. The baseline values for peak VO2 (p=0.656), PCS (p=0.582) and MCS (p=0.389) scores of quality of life did not differ between groups. Peak VO2 increased in exercise group and decreased in control group [mean difference of 3.509ml/kg/min; CI=95%; p<0.001]. PCS and MCS increased in exercise group and decreased in control group [mean difference of 10.86 and 14.78 respectively with CI=95% and p<0.001]. Conclusion: Exercise training had beneficial effect on cardiopulmonary function and overall quality of life in breast cancer females


for full paper please visit below link 

http://www.socialresearchfoundation.com/upoadreserchpapers/2/358/2007100949591st%20deepika%20dhamija.pdf

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